Causes of sarcopenia

Muscle loss in the elderly leads to a decline in mobility and independence. [1]

Sarcopenia is multifactorial in cause. These differing factors are inter-related and could contribute differently to the loss of muscle mass, muscle strength or muscle function. [1]

Of the contributory factors relating to the development of sarcopenia inadequate protein intake, increased splanchnic extraction of amino acids, decreased muscular response to postprandial anabolic stimuli and vitamin D deficiency are directly related to nutrition. [1]

Evidence suggests that most etiologic factors for sarcopenia are preventable and manageable with resistance training and adequate protein intake as key elements. [2]

The Society on Sarcopenia, Cachexia and Wasting Disorders (SCWD) recommend leucine-enriched balanced amino acid supplementation to enhance muscle strength. [3]