Clinical consequences of sarcopenia
A grave change associated with aging is progressive decline in skeletal muscle mass, a downward spiral that may lead to decreased strength and functionality .
The age-related loss of muscle mass, strength and function (sarcopenia) has a high clinical impact, and also affects your patients’ quality of life. 
- Cruz-Jentoft, A.J., et al., Age and Ageing, 2010. 39(4): p. 412-23.