* Energy Nutrient Dense Formula, Data on file.

Discover Infatrini: The most researched ENDF*, with clinically proven results

At Nutricia, we understand the critical importance of early growth and development in infants. Disruptions in an infants growth can significantly impact their development.1 That's why we've created Infatrini and dedicated over 15 years of research to explore it's safety and efficacy, a specially formulated ENDF designed to support the unique needs of infants experiencing faltering growth.

What is Infatrini?

Infatrini is a nutritionally complete ENDF formula offering a dietary management solution for infants with increased energy requirements, losses, or fluid restriction. It covers a wide range of conditions such as critical illnesses, infections, respiratory and GI disorders. Infatrini is designed to be used from birth and in young children up to 18 months (or 9kg) with disease related malnutrition and growth failure. As a ready to use liquid formula, it is suitable for administration via bottle and enteral feeding tubes.

*Long chain polyunsaturated fatty acids
Docosahexaenoic acid
Arachidonic acid

Nutritionally Complete3
Can be given:

  • as a sole source of nutrition for infants from birth and young children up to 18 months of age (or 9kg)
  • to complement breastfeeding
  • to supplement a poor oral intake

Energy Dense
1kcal/ml to address increased energy and nutrient requirements, fluid restrictions and/or limited ability to take oral feed2,4

Protein-Energy Ratio
2.6g protein / 100 ml (10.3% of energy) - higher P:E ratio, tailored for the nutritional needs of infants with faltering growth, in line with recommendations for lean mass desposition2,4

Additionally Contains: Prebiotic scGOS/lcFOS (9:1) and LCPUFAs

  • The most studied prebiotic mixture of oligosaccharides in infant formula, close to human milk oligosaccharides in quantity and diversity.14
  • Clinically demonstrated to increase numbers of bifidobacterial and reduce infections.5,6
  • Arachidonic acid (AA) and docosahexaenoic acid (DHA) at levels comparable to those of mature human milk.4,7

In which cases Infatrini might be used?

Why Choose Infatrini for Catch-up growth?

Infatrini's Transformative Impact

Promote Catch-Up Growth:
Infatrini is formulated to provide ~40% higher energy intake10 and 60% more weight gain per day compared to standard infant feeds11, ensuring malnourished or fluid-restricted infants receive the necessary support for rapid, quality catch-up growth.

Energy and protein targets met within 2 days

Infants receiving Infatrini had a significantly higher intake of nutrients after day 1 *12 compare infants receiving standard infant formula

Reaching growth targets in challenging patients

Infants receiving Infatrini demonstrated a significant increase in weight-for-age z score9

Reduces Hospital Stay & Antibiotic Use:

Additionally, it promotes faster recovery time, evidenced by reduced length of hospital stay and antibiotic use. This supports both patient outcomes and alleviates the burden on the healthcare system.

Composition for Enhanced Tolerance and Weight Gain:

Infatrini is well tolerated by 90% of critically ill patients. The low osmolality and unique prebiotic blend of scGOS/lcFOS (9:1) are engineered to ensure optimal tolerance and promote gut health. These features make it suitable even for the most sensitive infants, supporting a stable and healthy gut microbiome and reducing the risk of infections and gastrointestinal discomfort. The most important, the protein-energy ratio of 10.3% of energy from protein promotes growth of lean mass for high quality weight gain.

Consistently shown to be tolerated in a range of complex patients13

Infatrini appears to be well tolerated in infants when administered from day 1

Younger infants may benefit from a gradual introduction to Infatrini. However, for the majority of infants with faltering growht, Infatrini can be introduced at full strength from day 1.

Discover more on how Infatrini can help achieving catch-up growth in infants

Learn more about the pivotal role of Infatrini in paediatric nutritional care and recovery of infants. Explore further clinical evidence, that underscores Infatrini's commitment to supporting growth and development in infants when it matters most. Download the PDF to deep dive further into Infatrini’s impact on weight gain, nutritional intake, and overall tolerance.

Infatrini is an energy and nutrient dense, nutritionally complete feed for infants from birth and young children up to 18 months of age (or 9 kg) with disease related malnutrition and growth failure. Infatrini is a dietary food for special medical purposes (FSMP) and must be used under medical supervision.

  1. McDougall P et al. The detection of early weight faltering at 6-8-week check and its association with family factors, feeding and behavioural development. Arch Dis Child 2009;94:549-52.
  2. Joint WHO/FAO/UNU Expert Consultation. Protein and amino acid requirements in human nutrition. World Health Organ Tech Rep Ser. 2007;(935):1-265.
  3. Golden MH. Proposed recommended nutrient densities for moderately malnourished children. Food and Nutrition Bulletin, 2009; vol.30, no.3.
  4. Moro G et al. Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formulafed  term infants. J Pediatr Gastroenteral Nutr 2002; 34:291-5.
  5. Arslanaglu S el al. Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life. J Nutr 2008; 138: 1091-5.
  6. Brenna JT et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr 2007; 85:1457-1464
  7. Clarke SE et al. Randomized comparison of a nutrient-dense formula with an energy-supplemented formula for infants with faltering growth. J Hum Nutr Diet 2007;20:329-39.
  8. Eveleens RD et al. Weight improvement with the use of protein and energy enriched nutritional formula in infants with prolonged PICU stay. J Hum Nutr Diet 2019;32:3-10.
  9. Zhang H et al. High-energy nutrition in paediatric cardiac critical care patients: a randomized controlled trial. Nurs Crit Care 2018, Dec 9;
  10. Scheeffer VA et al. Tolerbility and Effects of the Use of Energy-Enriched Infant Formula After Congenital Heart Surgery: A Randomized Controlled Trial. JPEN. 2020;44(2),348-354. 
  11. Cui Y. et al. Effects and Tolerance of Protein and Energy-Enriched Formula in Infants Following Congenital Heart Surgery: A Randomized Controlled Trial. Journal of Parenteral and Enteral Nutrition 2018;42(1):196–204.
  12. Evans S et al. Should high-energy infant formula be given at full strength from its first day of usage? J Hum Nutr Diet. 2006;19(3):191-7.
  13. Salminen S et al. Infant Formula Supplemented with Biotics: Current Knowledge and Future Perspectives. Nutrients. 2020 Jun 30;12(7):1952
      

Do you need support?

Contact our team for guidance on the use and composition of our product range, to get in touch with your local Nutricia representative.

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